MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $338.1K of their own money on 862 shares at $392.
+$338.1K
862 sh @ $392
BAKER BROS. ADVISORS LP
Director, 10% Owner · SEC CIK 1263508
Insider at
PRLD Prelude Therapeutics Inc
INCY INCYTE CORP
DNLI Denali Therapeutics Inc.
ACAD ACADIA PHARMACEUTICALS INC
KNSA Kiniksa Pharmaceuticals International, plc
ONC BeiGene, Ltd.
TCRX TScan Therapeutics, Inc.
REPL Replimune Group, Inc.
DBVT DBV Technologies S.A.
BCYC BICYCLE THERAPEUTICS PLC
KOD Kodiak Sciences Inc.
KYMR Kymera Therapeutics, Inc.
TRDA Entrada Therapeutics, Inc.
KALA KALA BIO, Inc.
CELC Celcuity Inc.
VTVT vTv Therapeutics Inc.
MDGL MADRIGAL PHARMACEUTICALS, INC.
IGMS IGM Biosciences, Inc.
IMCR Immunocore Holdings plc
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Buy track record
How this insider's open-market purchases have performed70%
of buys now in profit
42 up · 18 down
Avg return since buy+12.3%
Median return+22.8%
Best trade+41.6%
Worst trade−29.6%
Buys scored60
Average return by holding period — separates good entry timing from riding one long winner
After 1 month
+14.9%
90% won · 60 trades
After 3 months
+37.8%
93% won · 60 trades
After 6 months
+11.8%
69% won · 58 trades
After 12 months
—
not elapsed yet
| Date | Company | 90d trend | Buy price | Value | ΔOwn | 1M | 3M | 6M | 12M | To date |
|---|---|---|---|---|---|---|---|---|---|---|
| Dec 18, 2025 | KOD | $23 | $5M | +16% | +1.0% | −16.3% | — | — | +29.1% | |
| Dec 18, 2025 | KOD | $23 | $55M | +15% | +1.0% | −16.3% | — | — | +29.1% | |
| Dec 11, 2025 | KYMR | $86 | $14.38M | +31% | −16.8% | −7.2% | −5.5% | — | −1.8% | |
| Dec 11, 2025 | KYMR | $86 | $158.12M | +30% | −16.8% | −7.2% | −5.5% | — | −1.8% | |
| Nov 20, 2025 | TRDA | $9 | $11K | +0.3% | +15.8% | +23.1% | −34.1% | — | −29.6% | |
| Nov 20, 2025 | TRDA | $9 | $121.4K | +0.3% | +15.8% | +23.1% | −34.1% | — | −29.6% | |
| Nov 20, 2025 | TRDA | $9 | $10.8K | +0.3% | +15.8% | +23.1% | −34.1% | — | −29.6% | |
| Nov 20, 2025 | TRDA | $9 | $118.7K | +0.3% | +15.8% | +23.1% | −34.1% | — | −29.6% | |
| Nov 12, 2025 | TRDA | $8 | $56.6K | +2.0% | +38.3% | +34.8% | −11.1% | — | −19.4% | |
| Nov 12, 2025 | TRDA | $8 | $625.3K | +1.8% | +38.3% | +34.8% | −11.1% | — | −19.4% | |
| Nov 12, 2025 | TRDA | $8 | $8.3K | +0.3% | +38.3% | +34.8% | −11.1% | — | −19.4% | |
| Nov 12, 2025 | TRDA | $8 | $91.4K | +0.2% | +38.3% | +34.8% | −11.1% | — | −19.4% | |
| Nov 11, 2025 | TRDA | $7 | $7.8K | +0.3% | +40.4% | +43.8% | −9.1% | — | −16.1% | |
| Nov 11, 2025 | TRDA | $7 | $86.5K | +0.3% | +40.4% | +43.8% | −9.1% | — | −16.1% | |
| Nov 11, 2025 | TRDA | $8 | $21.1K | +0.8% | +40.4% | +43.8% | −9.1% | — | −16.1% | |
| Nov 11, 2025 | TRDA | $8 | $232.8K | +0.7% | +40.4% | +43.8% | −9.1% | — | −16.1% | |
| Nov 10, 2025 | TRDA | $7 | $16.6K | +0.6% | +45.9% | +49.0% | −3.6% | — | −11.0% | |
| Nov 10, 2025 | TRDA | $7 | $183K | +0.6% | +45.9% | +49.0% | −3.6% | — | −11.0% | |
| Nov 10, 2025 | TRDA | $7 | $1.9K | +0.1% | +45.9% | +49.0% | −3.6% | — | −11.0% | |
| Nov 10, 2025 | TRDA | $7 | $21.3K | +0.1% | +45.9% | +49.0% | −3.6% | — | −11.0% | |
| Sep 8, 2025 | CELC | $56 | $785.7K | +2.0% | −20.8% | +66.4% | +81.4% | — | +41.6% | |
| Sep 8, 2025 | CELC | $56 | $8.52M | +2.1% | −20.8% | +66.4% | +81.4% | — | +41.6% | |
| Sep 8, 2025 | CELC | $58 | $22.5K | +0.1% | −20.8% | +66.4% | +81.4% | — | +41.6% | |
| Sep 8, 2025 | CELC | $58 | $244.4K | +0.1% | −20.8% | +66.4% | +81.4% | — | +41.6% | |
| Aug 20, 2025 | MDGL | $380 | $182.6K | +0.2% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $380 | $1.98M | +0.3% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $381 | $67K | +0.1% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $381 | $730.7K | +0.1% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $381 | $332.7K | +0.4% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $381 | $3.61M | +0.5% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $382 | $40.1K | +0.1% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $382 | $434.3K | +0.1% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $383 | $100.3K | +0.1% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $383 | $1.09M | +0.1% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $384 | $143.2K | +0.2% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $384 | $1.55M | +0.2% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $385 | $480.6K | +0.6% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $385 | $5.22M | +0.7% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $387 | $158.3K | +0.2% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $387 | $1.72M | +0.2% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $389 | $13.2K | — | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $389 | $142.4K | — | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $390 | $90.1K | +0.1% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $390 | $977.1K | +0.1% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $392 | $338.1K | +0.4% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 20, 2025 | MDGL | $392 | $3.67M | +0.5% | +12.4% | +38.4% | +11.1% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $373 | $917.3K | +1.3% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $373 | $9.96M | +1.4% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $374 | $252.7K | +0.3% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $374 | $2.74M | +0.4% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $354 | $62.6K | +0.1% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $354 | $680.5K | +0.1% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $355 | $29.8K | — | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $355 | $325.2K | +0.1% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $357 | $273.8K | +0.4% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $357 | $2.97M | +0.5% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $358 | $81.7K | +0.1% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $358 | $885.5K | +0.1% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $359 | $281.8K | +0.4% | +12.6% | +42.8% | +25.6% | — | +22.8% | |
| Aug 18, 2025 | MDGL | $359 | $3.06M | +0.5% | +12.6% | +42.8% | +25.6% | — | +22.8% |
How this is calculated. We score only open-market purchases (SEC code
P) — the buys that carry real signal. Each trade's return is measured from the adjusted closing price on the purchase date to the latest close, accounting for stock splits and dividends. The 1M/3M/6M/12M columns show the same trade's return after each fixed holding period; a dash means that horizon hasn't elapsed yet or isn't priceable. Sales are excluded because insiders sell for many routine reasons. With only 60 scored trades, treat this as a small sample, not a verdict.
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Open-market buys
$334.45M
80 trades
Open-market sells
$1.19M
6 trades
Net flow
+$333.26M
Net buying
Total filings
105
transactions shown
Full transaction history
All Form 4 activity across every company, newest firstMDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $3.67M of their own money on 9,362 shares at $392.
+$3.67M
9,362 sh @ $392
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $917.3K of their own money on 2,460 shares at $373, growing their stake 1%.
+$917.3K
2,460 sh @ $373
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $9.96M of their own money on 26,704 shares at $373, growing their stake 1%.
+$9.96M
26,704 sh @ $373
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $252.7K of their own money on 675 shares at $374.
+$252.7K
675 sh @ $374
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MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $2.74M of their own money on 7,325 shares at $374.
+$2.74M
7,325 sh @ $374
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $62.6K of their own money on 177 shares at $354.
+$62.6K
177 sh @ $354
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $680.5K of their own money on 1,923 shares at $354.
+$680.5K
1,923 sh @ $354
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $29.8K of their own money on 84 shares at $355.
+$29.8K
84 sh @ $355
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $325.2K of their own money on 916 shares at $355.
+$325.2K
916 sh @ $355
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $273.8K of their own money on 767 shares at $357.
+$273.8K
767 sh @ $357
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $2.97M of their own money on 8,328 shares at $357.
+$2.97M
8,328 sh @ $357
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $81.7K of their own money on 228 shares at $358.
+$81.7K
228 sh @ $358
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $885.5K of their own money on 2,472 shares at $358.
+$885.5K
2,472 sh @ $358
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $281.8K of their own money on 784 shares at $359.
+$281.8K
784 sh @ $359
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $3.06M of their own money on 8,514 shares at $359.
+$3.06M
8,514 sh @ $359
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $181.4K of their own money on 502 shares at $361.
+$181.4K
502 sh @ $361
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $1.97M of their own money on 5,443 shares at $361.
+$1.97M
5,443 sh @ $361
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $186.6K of their own money on 515 shares at $362.
+$186.6K
515 sh @ $362
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $2.02M of their own money on 5,587 shares at $362.
+$2.02M
5,587 sh @ $362
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $92.8K of their own money on 255 shares at $364.
+$92.8K
255 sh @ $364
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $1.01M of their own money on 2,772 shares at $364.
+$1.01M
2,772 sh @ $364
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $77.3K of their own money on 211 shares at $366.
+$77.3K
211 sh @ $366
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $838.5K of their own money on 2,289 shares at $366.
+$838.5K
2,289 sh @ $366
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $162.6K of their own money on 442 shares at $368.
+$162.6K
442 sh @ $368
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $1.76M of their own money on 4,798 shares at $368.
+$1.76M
4,798 sh @ $368
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $48.3K of their own money on 131 shares at $369.
+$48.3K
131 sh @ $369
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $523.4K of their own money on 1,419 shares at $369.
+$523.4K
1,419 sh @ $369
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $93.4K of their own money on 253 shares at $369.
+$93.4K
253 sh @ $369
MDGL
Baker Bros. Advisors Lp, MDGL's Director, spent $1.01M of their own money on 2,747 shares at $369.
+$1.01M
2,747 sh @ $369
Frequently asked questions
How is BAKER BROS. ADVISORS LP's win rate calculated?
We take every open-market purchase (SEC code P) we can match to a stock price, then compare the split- and dividend-adjusted price on the purchase date to the most recent close. The win rate is the share of those buys currently trading above the purchase price. Sales and share grants are not scored.
Why are some buys not included in the score?
A purchase is excluded if we can't price it — for example if the ticker is missing from the filing, the company has been delisted, or the security isn't a common stock we can match to market data. Excluded counts are shown next to the scored total.
What do the 1M / 3M / 6M / 12M columns mean?
They show each purchase's return after a fixed holding period — one, three, six, and twelve months from the buy date — using split- and dividend-adjusted prices. This separates good entry timing from simply holding a long-running winner. A dash means that horizon hasn't elapsed yet for that trade, or the stock couldn't be priced at that date.
Does a high win rate mean I should copy this insider?
No. Past performance does not predict future results, sample sizes are often small, and an insider's edge in their own company doesn't transfer to yours. This is context, not a recommendation. InsiderSource is not investment advice.
Where does this data come from?
Trades come from BAKER BROS. ADVISORS LP's SEC Form 4 filings on EDGAR. Prices come from public market data and are split/dividend-adjusted. Always verify against the original filings before acting.